Differin (Adapalene) 0.1% Gel for Acne

Treatment Details

Treatment Details
Overview
Side Effects
Directions
More Information

What is Differin and what is it used for?
Differin Cream and Gel are both prescription acne treatments that are applied directly to the skin, making Differin a great choice for people who cannot or who do not wish to take oral antibiotics. The active ingredient Adalpalene is effective at reducing inflammation helping to improve the appearance of blackheads, whiteheads, and pustules on the skin.
Differin once daily Cream and Gel are manufactured by Galderma and are available in 45-gram tubes for mild to moderate acute acne. Most people will notice an improvement to their skin in just a few weeks, however, Differin must be used daily for a full 3 months. Differin can be combined with a topical or oral antibiotic for more severe acne.
How Differin gel works
The active ingredient in Differin, Adapalene, is a form of vitamin A and it works to reduce the growth of keratin surface skin cells that can block pores. Sebum is a natural, oily substance produced by glands just under the surface of the skin called sebaceous glands, needed to keep the skin smooth and supple. Sufferers of acne often produce too much sebum, which can mix with the dead keratin skin cells and cause the pores to become blocked.
Blocked pores can then lead to the formation of spots, blackheads (comedones) and whiteheads. Applying Differin 0.1% Cream to the affected areas will help reduce the amount of keratin skin cells and unblock the pores and sebaceous glands, allowing the sebum to escape. This will result in a reduction of inflammation, whiteheads, comedones and spots.
Differin 0.1% cream/gel is also beneficial as it increases the natural turnover of the skin cells. This aids the natural exfoliation of the skin’s outer layers. This action will help keep pores unblocked, thus reducing the formation of spots and blackheads

Type of medicine	Topical retinoid
Works by	Removing dead skin cells from the surface of the skin
Active ingredient	Adapalene
Strength	0.1%
Effective within	3 - 6 months of regular use
Pack size	45g
Generic	No
Use with alcohol	No known issues

Like all topical applications, there is the potential that you may be allergic to Differin. We recommend you do a spot test before commencing treatment.
If you do experience side effects from Differin cream/gel, they can include:
· a burning, stinging or tingling feeling
· dry skin
· itching or redness
· a rash
For more information and make sure to read the Patient Information Leaflet enclosed with your medicines for a full list of side effects, before applying.
It is usually well-tolerated and gets positive ratings from patients who review Differin.
If you experience any adverse effects from taking your prescribed medicine it is important to let us know immediately or your contact your GP.
How to use Differin
Differin cream/gel should be applied to the affected areas once daily in the evening, after washing with a mild cleanser.
Apply a small amount to cover the affected areas using clean fingertips and rub in lightly.
At the start of treatment with Differin, if it is used correctly it will produce effects similar to that of mild sunburn including mild itching, redness and warmth. This is normal and should subside.
To get the best effects from Differin cream/gel it is important that it is for up to THREE months continuously depending on response. Improvement should be seen after a few weeks. This period is called the ‘Differin purge’.
You may use cosmetics and moisturisers whilst you are using Differin cream however you should wait for it to be fully absorbed into the skin before applying anything else. Differin has a drying effect on the skin so it is important to try to ensure that any toiletries containing alcohol or other skin-drying ingredients are not used.
PIL: https://www.medicines.org.uk/emc/files/pil.921.pdf

Frequently asked questions

What is Differin used for?
Differin is used to treat acne by reducing inflammation and improving the appearance of blackheads, whiteheads, and pustules on the skin.
How does Differin work?
Differin contains adapalene, a form of vitamin A, which helps reduce the growth of keratin surface skin cells that can block pores, leading to acne.
Is Differin effective for acne?
Yes, Differin is effective for mild to moderate acne. Most people notice an improvement in their skin within a few weeks of regular use.
Can Differin be used with other acne treatments?
Yes, Differin can be combined with other topical or oral acne treatments, but it's best to consult with a healthcare professional before doing so.
How long should I use Differin?
Differin should be used daily for a full 3 months to see the best results. Improvement in acne should be seen after a few weeks.
Can Differin cause side effects?
Common side effects of Differin may include burning, stinging, dryness, itching, or redness. These side effects usually subside with continued use.
Is Differin available over the counter?
Differin is available by prescription only and should be used under the guidance of a healthcare professional.
Can Differin help with acne scars?
While Differin is primarily used to treat active acne, some people find that it also helps diminish the appearance of acne scars over time.
Can I use Differin if I have sensitive skin?
People with sensitive skin may experience more irritation when using Differin. It's advisable to start with a lower concentration and gradually increase as tolerated.
Is Differin safe to use during pregnancy?
It's important to consult with a healthcare professional before using Differin during pregnancy or breastfeeding to weigh the potential risks and benefits.