Foundayo at Curely

Treatment Details

Treatment Details
Overview
Side Effects of Foundayo
Directions
More Information
Ingredients

What is Foundayo?
Foundayo is the brand name for the orforglipron pill, a once-daily oral GLP-1 receptor agonist developed for weight management.
It comes as a tablet you take once a day, making it an option for people who prefer an oral treatment over weight loss injections .
Doctors recommend taking Foundayo alongside a reduced-calorie diet and increased physical activity.
How Does Foundayo Work?
Orforglipron is a GLP-1 (glucagon-like peptide-1) receptor agonist. GLP-1 is a naturally occurring hormone that regulates appetite and blood sugar. By activating the receptors, Foundayo can help:
- Reduce appetite and hunger
- Increase feelings of fullness after eating
- Reduce overall calorie intake
- Support blood sugar regulation
- Promote long-term weight loss
How Effective is the Foundayo Weight Loss Pill?
According to the 72-week ATTAIN-1 clinical trial, average body weight reductions were approximately:
- 7.4% with 5.5 mg
- 8.3% with 9 mg
- 11.1% with 17.2 mg
In the ATTAIN-1 Phase 3 clinical trial, participants lost 12.4 kg (12.4% of body weight) at 72 weeks.
However, note that individual results vary depending on factors such as your starting body weight and how you respond to the medication.
Benefits of Foundayo
Foundayo may offer several benefits including:
- Clinically proven weight loss
- Convenience of no injections or needles
- Flexible dosing where you can take it at any time of the day, with or without food
- Waist size reduction
- Metabolic improvements such as lower blood pressure
Who Can Take Foundayo for Weight Loss?
Foundayo is a prescription-only medicine that you should only get after an appropriate clinical assessment.
The medication is licensed for weight management in adults with obesity (BMI 30+), or adults who are overweight (BMI 27 to 29.9) and have at least one weight-related medical condition such as high blood pressure or sleep apnoea.
Our prescribing clinician will thoroughly assess your BMI, medical history, current medication, previous weight loss treatment, and overall health before prescribing Foundayo.

Type of Medicine	GLP-1 weight loss medication
Works By	Activates GLP-1 receptors to reduce hunger and increase fullness.
Active Ingredient	Orforglipron
Availability	Prescription only
Pack Size	Varies
Strength	0.8 mg 2.5 mg 5.5 mg 9 mg 14.5 mg 17.2 mg
Dosage Form	Tablets
Common Side Effects	Nausea Constipation Diarrhoea Vomiting Indigestion Stomach pain
Use With Alcohol	No specific interaction is known, but alcohol may worsen some gastrointestinal side effects.

Common Foundayo Side Effects
- Nausea
- Constipation
- Diarrhoea
- Vomiting
- Indigestion
- Abdominal pain or discomfort
- Bloating
- Acid reflux or heartburn
- Burping
- Flatulence
- Headache
- Fatigue
- Hair loss
Rare But Serious Side Effects
- Pancreatitis: It causes severe and persistent abdominal pain that spreads towards your back, with or without nausea or vomiting.
- Severe Gastrointestinal Problems: Persistent stomach problems such as continuous vomiting and abdominal pain that doesn't go away.
- Kidney Problems: Persistent vomiting or diarrhoea can cause dehydration and potentially affect kidney function.
- Low Blood Sugar: The risk of hypoglycaemia can be higher when you use Foundayo alongside certain diabetes medicines, such as insulin and sulfonylureas.
- Serious Allergic Reactions: Some people experience swelling of the face, lips, tongue, or throat. Other signs of allergic reactions include difficulty breathing or swallowing, a severe rash, and fainting.
Stop taking Foundayo and seek medical advice if you develop any of these symptoms.
How to Take Foundayo
Always take the medication according to your prescriber’s instructions, which are often as follows:
1. Take one Foundayo tablet once each day.
2. You can take the pill with or without food.
3. Swallow the tablet whole.
4. Do not break, crush, or chew the tablet.
5. Do not take more than one tablet in the same day.
Treatment normally begins with the 0.8 mg pill. Your prescriber may then gradually increase your dose depending on weight loss progress and goals.
What Happens if I Miss a Dose?
- Take the missed tablet as soon as you remember.
- Do not take two Foundayo tablets on the same day to make up for a missed dose.
- Speak to your prescribing clinician if you’ve missed Foundayo doses for 7 days or more. Your clinician may need to review your prescription before you can continue with the medication.
Can I Switch from Mounjaro or Wegovy to Foundayo?
Yes, but always do it with the help of a prescriber such as Curely. Avoid switching treatments yourself or taking Foundayo at the same time as another GLP-1 receptor agonist.
If you’re currently taking Mounjaro , Wegovy , or another weight loss pill , tell your Curely clinician during consultation.
Who Should Avoid Taking Foundayo?
Foundayo isn’t suitable for everyone. The following categories of people should avoid or take caution before using the medication:
- Personal or Family History of Medullary Thyroid Carcinoma (MTC): Anyone with a history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Known Hypersensitivity: Anyone with a known severe allergic reaction to orforglipron or any of the inactive ingredients in the tablet.
- Pregnant, Planning to Become Pregnant, or Breastfeeding: Weight loss can harm a developing fetus, and there’s no safety information on Foundayo during breastfeeding.
- Severe Liver Impairment: Not recommended for patients with chronic liver disease.
- Serious Stomach Conditions: People with progressed gastroparesis (slow stomach emptying) or other digestive issues should avoid Foundayo or take caution.
- History of Pancreatitis: Patients with a history of acute or chronic inflammation of the pancreas should proceed with extreme caution.
- Concurrent Other GLP-1 Medications: Avoid combining Foundayo with other GLP-1 receptor agonists such as Wegovy, Zepbound, and Mounjaro.
Buy the Foundayo Pill Online in the UK
Foundayo is a prescription-only medicine that requires a thorough clinical assessment by a qualified prescriber. Avoid buying Foundayo or other prescription weight loss medicines from an unregulated website or seller.
Complete an online consultation through Curely's weight management service. A qualified clinician will go through your answers before deciding whether Foundayo is suitable for you.
If approved, we’ll dispense your Foundayo prescription and deliver the medication in discreet packaging to your chosen address.
Start your consultation today.
Shipping Info
Fast, Free & Discreet Delivery
Curely offers free tracked delivery on every order, giving you a quick and reliable way to receive your medication.
Next-Day Delivery Cut-Off Times
Need your medication quickly? Place your order before 12:00 pm, Monday to Friday, to qualify for next-day delivery.
We deliver Monday to Saturday.
Discreet Packaging Guaranteed
Curely puts your privacy first. That’s why we use plain, unbranded packaging for all orders.
- No Curely branding
- No pharmacy labels
- No product names
We never use the Curely brand name on bills, delivery paperwork, or your bank statement. You’ll simply receive a plain package straight to your door, keeping everything private.
Secure, Hassle-Free Payments
Curely offers a range of safe payment options, making it easy to complete your purchase. Choose the payment method that works for you, and we’ll process your order quickly and securely.
References
- Eli Lilly: Foundayo (orforglipron) prescribing information and patient site.
- Wharton S, et al. Orforglipron, an Oral GLP-1 Receptor Agonist for Obesity Treatment, New England Journal of Medicine 2025.
- Horn DB, et al. Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2), The Lancet, 2025.
Active Ingredient
Orforglipron
Inactive Ingredients
- Copovidone
- Crospovidone
- Magnesium stearate
- Microcrystalline cellulose
- Sodium carbonate anhydrous

Frequently asked questions

Is Foundayo available in the UK?
Foundayo (orforglipron) is a prescription-only weight loss medicine. Availability through Curely will depend on UK supply and stock availability. You can join the Curely Foundayo priority list to receive updates when Foundayo becomes available to order.
How much will Foundayo cost in the UK?
The price of Foundayo will depend on the tablet strength prescribed and UK supply arrangements. Curely aims to offer competitive pricing across its weight loss treatments. Join our Foundayo priority list to receive launch, availability and pricing updates.
When will Foundayo be available to buy from Curely?
Curely plans to make Foundayo available to eligible patients subject to stock availability and clinical prescribing requirements. Join the Foundayo priority list and we will let you know when Foundayo is available through Curely.
Is Foundayo a tablet or an injection?
Foundayo is a weight loss tablet, not an injection. It contains orforglipron, an oral GLP-1 receptor agonist. Patients take Foundayo once a day, making it an option for people who want GLP-1 weight loss treatment without injections or needles.
How quickly does Foundayo start working?
Foundayo begins acting on GLP-1 receptors after taking your first dose. How quickly you notice changes in appetite varies, but it usually happens within the first one to two weeks. Weight loss occurs gradually, with visible results appearing after a few months of taking the pill.
How much weight can you lose with Foundayo?
Weight loss with Foundayo varies between individuals and depends on factors including your dose, starting weight, diet, physical activity and response to treatment.
In the 72-week ATTAIN-1 clinical trial, participants taking the 17.2 mg dose achieved an average body weight reduction of approximately 11.1%. Lower doses also produced clinically meaningful weight loss.
These figures are averages from clinical trials and do not guarantee how much weight an individual patient will lose.
Do you need a prescription for Foundayo in the UK?
Yes. Foundayo is a prescription-only medicine and cannot be legally supplied in the UK without an appropriate prescription.
When available through Curely, you will need to complete a clinical assessment. A qualified prescribing clinician will review your BMI, medical history, current medicines and other relevant information before determining whether Foundayo is suitable for you.
Can I take Foundayo with food?
Yes. Foundayo can be taken with or without food, giving you flexibility over when you take your daily tablet.
Take Foundayo once a day as directed by your prescriber and swallow the tablet whole. You should not crush, chew or split the tablet.
Do I Need to Keep Foundayo in the Fridge?
No, you can store Foundayo at room temperature. Always check the patient information leaflet for the manufacturer's storage instructions.
Is Foundayo better than Mounjaro for weight loss?
Clinical trials for Mounjaro show results of about 22% body weight loss, which is higher than Foundayo. However, orforglipron may be more convenient for people who are uncomfortable with injections since there’s no Mounjaro pill. The best weight loss treatment for you will depend on your medical history, goals, previous medications, response, and personal preferences.